Endocrine Abstracts

35-year-old lady, has a background of Hypertension, oophorectomies for ovarian cancer and previous 2 IVF attempts, referred to endocrinology with three-week history of blurred vision, bitemporal hemianopia and large pituitary mass on MRI Upon assessment, she reported visual disturbance and intermittent headache. She has no periods which is expected with the history of oophorectomy, but she denied galactorrhoea or any symptoms suggestive of pituitary hormone excess or deficienc...

Case summary: A 40 year-old lady, who has a background of asthma, presented to emergency department with back pain radiated down to her left leg with associated foot drop. She also complained of 2 months history of weight gain, hirsutism, and menstrual disturbance. Clinical examination confirmed that she had some cushingoid features. Further assessment and investigations revealed that she had acute disc prolapse on MRI as well as an incidental finding of right adrenal gland an...

Introduction: Hypercalcemia has been described in patients with granulomatous disorders. Most commonly sarcoidosis (10% of patients) and tuberculosis with three-fold increase in hypercalciuria. It’s due to production of calcidiol from calcitriol in the lung and lymph nodes that is independent of PTH. Main modalities of therapy are low-calcium diet, glucocorticoids, and treatment of the underlying disease.The Case: A 48-year-old male, referred to end...

Introduction: Vitamin D toxicity (VDT) is quite an uncommon condition which results from misperception between dosage regimens of vitamin D supplementation. VDT is diagnosed when Serum 25-hydroxyvitamin D levels are higher than 375 nmol/l (150 ng/ml). Vitamin D supplementation is easily accessible as over-counter medication and online. This report describes a patient who presented with severe hypercalcemia and acute kidney injury (AKI). Further assessment revealed that patient...

A 91-year-old lady presented with bradycardia ‘HR ~36, she was alert and conscious initially. Soon after the initial assessment, she was found unresponsive; with blood glucose of 0.8 mmol/l; bradyapnoec; BP 151/59; GCS 5/15; temp ‘32.8°C’. She was aroused after resuscitation with intravenous Dextrose, GCS 15/15 with an element of confusion, the temperature did not exceed 34.9°C despite active warming. The patient looked in a low mood, barely audible, w...